Antioxidants are substances, either natural or manufactured, that may prevent or limit cell damage caused by unstable particles called free radicals. Antioxidants work by neutralizing free radicals -- giving them electrons. Antioxidants may also be able to undo some cell damage.[1,2,4]
Types of antioxidants
Vitamin A, vitamin C, vitamin E, selenium, lycopene, and beta-carotene are examples of antioxidants.
Free radicals
Free radicals are groups of atoms that are produced when oxygen interacts with certain molecules, thereby setting off a chain reaction. Their primary danger comes from the damage caused when they react with DNA, and other cell components. Cells can die off, or stop functioning correctly, when this occurs. Antioxidants are the body's defense system against free radical damage.
Free radicals can be formed by:
- Sun exposure
- Cigarette smoke
- Alcohol consumption
- Air pollution
- Exercise
- Inflammation
- Drug abuse
Cells damaged by free radicals may be at risk for developing cancer, heart disease, and diabetes.[1]
Sources
The body makes some antioxidants and gets others from food to combat free radicals.[4] It's important to eat a well-balanced diet to help you get the antioxidants you need.
Good sources of antioxidants
Category | Examples |
---|---|
Fruit | Strawberries, oranges, cantaloupe, watermelon |
Vegetables | Broccoli, tomatoes, kale, carrots |
Dairy | Milk, butter, eggs |
Meat | Fish, chicken, beef, turkey |
Legumes and oils | Nuts, seeds, oils, sunflower seeds, almonds, peanuts, corn oil |
Carbohydrates | Bread and pasta |
Cereals | Whole wheat, rice, corn |
Supplements can also be a good source of antioxidants.
Do antioxidants work
Although eating fruits and vegetables can help lower the risk of developing certain diseases, researchers can't tell for sure if the presence of antioxidants is the reason. It could also be that people who eat more fruits and vegetables also have a healthier lifestyle, eat healthier overall, exercise, and don't smoke.[2]Many well-organized studies, involving numerous subjects, have looked at the effect of antioxidant supplements on diseases, such as cardiovascular disease, cancer, and cataract prevention.They found that overall, antioxidants are not beneficial.[2]
But, the Age-Related Eye Disease Study (AREDS), led by the National Eye Institute and co-sponsored by the National Institutes of Health, found that antioxidant supplementation could be beneficial. Researchers discovered that a combination of antioxidants (vitamin C, vitamin E, and beta-carotene) and zinc significantly reduced the risk of developing advanced-stage, age-related macular degeneration (ARMD) for people who had intermediate stage (ARMD) and advanced stage in only one eye.
However, the use of antioxidants without zinc was less effective and the antioxidants didn't effect cataract development.[2, 4]
More research is being done to discover antioxidants' effects on Alzheimer's disease, breast, and prostate cancers.[2]
Each antioxidant is different, so getting one or two types is not enough. They work together to provide better all-round health. That's why healthy eating, including a variety of fruits and vegetables, whole grains, and healthy fats from nuts, seeds, and oils, still beats supplements -- even in high doses -- in helping to prevent disease.[2]
Drug interactions
Antioxidants may interact with some medications, potentially altering their effects. Do not take vitamin E if you are on blood thinners as they may cause bleeding. Ask your doctor before taking antioxidants if you are undergoing cancer treatment.[2]
Safety issues and other considerations
References
FamilyDoctor.org; "Antioxidants: What You Need to Know;" 2010
National Center for Complementary and Alternative Medicine; "Antioxidants and Health: An Introduction;" Get the Facts; National Institutes of Health;" Updated 2012
National Cancer Institute; "Antioxidants and Cancer Prevention Fact Sheet"
Harvard School of Public Health; "Antioxidants: Beyond the Hype"
Rice; "Antioxidants and Free Radicals; Updated 1996
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- Mar 25, 2025Hi-Tech Pharmaceuticals CoQ10 120 Tablets (only 200mg) dropped by 20.8% to $42.74 at iHerb.com
- Mar 25, 2025Nutricost Lycopene 60 Softgels (only 20mg) dropped by 10.2% to $12.75 at Amazon
- Mar 25, 2025Nutricost Lycopene 60 Softgels (only 50mg) dropped by 10% to $19.75 at Amazon
- Mar 25, 2025Swanson Policosanol 60 Capsules (only 10mg) dropped by 10.1% to $4.44 at iHerb.com
- Mar 25, 2025Swanson Gamma Oryzanol 90 Vcaps dropped by 15% to $9.52 at iHerb.com
- Mar 25, 2025Jarrow Formulas QH-absorb 30 Softgels dropped by 33.2% to $26.90 at Amazon
- Mar 24, 2025NOW CoQ10 100 Softgels dropped by 8.3% to $15.99 at Muscle and Strength
- Mar 24, 2025Healthy Origins CoQ10 150 Softgels (only 100mg) dropped by 18.5% to $21.99 at Amazon
- Mar 24, 2025Healthy Origins Pycnogenol 120 Vcaps (only 150mg) dropped by 14% to $94.99 at Amazon
- Mar 24, 2025Healthy Origins Lycopene 180 Softgels dropped by 7.1% to $29.99 at Amazon
- Mar 24, 2025Solaray Lutein Eyes Advanced 60 Vcaps dropped by 19.1% to $44.00 at Amazon
- Mar 23, 2025Mason Naturals CoQ10 30 Softgels (only 100mg) dropped by 9.5% to $15.69 at VitaCost.com
- Mar 23, 2025Source Naturals Resveratrol 100 Tablets dropped by 7.4% to $8.79 at VitaCost.com
- Mar 23, 2025Source Naturals Policosanol 120 Tablets dropped by 9.7% to $13.89 at VitaCost.com
- Mar 23, 2025Nature's Way Tart Cherry Ultra 75 Gummies dropped by 10% to $14.82 at iHerb.com
- Mar 23, 2025Source Naturals Ubiquinol CoQH 60 Softgels (only 100mg) dropped by 25% to $32.02 at iHerb.com
- Mar 23, 2025Quality of Life CoQ10-SR 60 Vcaps dropped by 15% to $24.20 at iHerb.com
- Mar 23, 2025Swanson Mangosteen 90 Capsules dropped by 25% to $12.25 at iHerb.com
- Mar 22, 2025Swanson Naringin 60 Capsules dropped by 18.1% to $9.40 at iHerb.com
- Mar 22, 2025Swanson Sage Extract 100 Capsules dropped by 40.1% to $5.98 at iHerb.com
- Mar 22, 2025The Vitamin Shoppe CoQ-10 60 Softgels (only 200mg) dropped by 54.1% to $13.75 at Walmart
- Mar 22, 2025NOW CoQ10 150 Softgels (only 100mg) dropped by 8.1% to $32.58 at iHerb.com
- Mar 22, 2025NOW CoQ10 Antioxidant Serum 1 Oz. dropped by 10% to $12.55 at iHerb.com
- Mar 22, 2025Swanson Q-Gel Mega 30 Softgels dropped by 56.7% to $9.60 at iHerb.com
- Mar 21, 2025Country Life Resveratrol Plus 120 Vcaps dropped by 6.7% to $27.99 at AllStarHealth
- Mar 21, 2025Swanson Pomegranate Extract 60 Capsules dropped by 10% to $8.28 at iHerb.com
- Mar 20, 2025Country Life Maxi-Sorb Mega CoQ10 60 Softgels dropped by 9.4% to $60.00 at Amazon
- Mar 20, 2025GNC Alpha Lipoic Acid 60 Capsules (only 300mg) dropped by 15% to $16.99 at GNC
- Mar 20, 2025Nutricost Alpha Lipoic Acid 240 Capsules dropped by 14.5% to $23.70 at iHerb.com
- Mar 20, 2025Swanson Pycnogenol Wrinkle Cream 2 Oz. dropped by 10% to $10.68 at iHerb.com
- Mar 20, 2025Mary Ruth's CoQ10 Liposomal 7.6 Oz. dropped by 8.3% to $25.64 at iHerb.com
- Mar 18, 2025Force Factor Test X180 Ignite 120 Capsules dropped by 10.9% to $26.00 at Amazon
- Mar 18, 2025The Vitamin Shoppe Lutein with Zeaxanthin 60 Softgels dropped by 14.5% to $25.64 at iHerb.com
- Mar 18, 2025Life Extension Super R-Lipoic Acid 60 Vcaps dropped by 24.1% to $24.60 at Walmart
- Mar 18, 2025Swanson Ultimate Ocular Antioxidant 30 Softgels dropped by 11.8% to $16.45 at iHerb.com
- Mar 18, 2025Force Factor CoQ10 60 Vcaps dropped by 30.7% to $9.00 at Amazon
- Mar 18, 2025MRM CoQ-10 L-Carnitine 16 Oz. (only Cherry Pomegranate) dropped by 37.6% to $29.95 at Amazon
- Mar 17, 2025Nature's Way Tart Cherry Ultra 90 Chewables (only Montmorency Cherry) dropped by 60.9% to $7.67 at AllStarHealth
- Mar 17, 2025Hi-Tech Pharmaceuticals CoQ10 120 Tablets (only 100mg) dropped by 20.8% to $27.78 at iHerb.com
- Mar 16, 2025Nature's Plus Ultra Lipoic 60 Tablets dropped by 11.7% to $25.00 at AllStarHealth
- Mar 16, 2025Olympian Labs Alpha Lipoic CoQ10 60 Vcaps dropped by 31.6% to $5.20 at AllStarHealth
- Mar 16, 2025The Vitamin Shoppe Astaxanthin 30 Softgels dropped by 21.3% to $19.66 at iHerb.com
- Mar 16, 2025SNS Amentoflavone XT 60 Vcaps dropped by 6.3% to $22.95 at DPS Nutrition
- Mar 16, 2025Swanson Seaweed Vegetable Complex 60 Vcaps dropped by 10% to $10.85 at iHerb.com
- Mar 15, 2025Irwin Naturals Acai Berry Super-Cleanse 60 Softgels dropped by 10% to $17.99 at Best Price Nutrition
- Mar 15, 2025Nootropics Depot Tart Cherry 120 Tablets dropped by 20.8% to $39.99 at Amazon
- Mar 14, 2025Swanson Alpha Lipoic Acid 60 Capsules (only 600mg) dropped by 6.9% to $14.41 at Walmart
- Mar 14, 2025Swanson Super Green Max Plus Powder 9 Oz. dropped by 9.1% to $31.08 at Walmart
- Mar 11, 2025NOW Natural Resveratrol 60 Vcaps (only 200mg) dropped by 13.4% to $14.79 at AllStarHealth
- Mar 11, 2025Doctor's Best Lutein 60 Softgels (only with FloraGLO 20mg) dropped by 6.4% to $7.70 at AllStarHealth
- Mar 11, 2025Jarrow Formulas Alpha Lipoic Acid with Biotin 60 Vcaps dropped by 56.4% to $10.40 at AllStarHealth
- Mar 10, 2025Nature's Way Resveratrol Forte 60 Softgels dropped by 15% to $25.51 at iHerb.com
- Mar 10, 2025Nature's Way CoQ10 120 Softgels dropped by 25% to $39.82 at iHerb.com
- Mar 10, 2025Olympian Labs Grape Seed Extract 100 Vcaps (only 200mg) dropped by 17.6% to $19.61 at iHerb.com
- Mar 09, 2025NOW Quercetin Phytosome 90 Vcaps dropped by 7.3% to $20.49 at AllStarHealth
- Mar 08, 2025Swanson Super Fruit Complex, Full Spectrum 90 Capsules dropped by 7.4% to $12.41 at Amazon
- Mar 08, 2025Life Extension Resveratrol Elite 30 Vcaps dropped by 7.5% to $11.24 at Amazon
- Mar 08, 2025Swanson Resveratrol & Quercetin 30 Vcaps dropped by 9.9% to $17.38 at iHerb.com
- Mar 07, 2025Doctor's Best High Absorption CoQ10 180 Vcaps (only 400mg) dropped by 30.3% to $53.90 at AllStarHealth
- Mar 07, 2025MRM CoQ-10 120 Softgels dropped by 72.6% to $7.90 at AllStarHealth
- Mar 07, 2025MacroLife Naturals Miracle Reds 30 Servings dropped by 22.2% to $39.99 at AllStarHealth
- Mar 07, 2025NOW Quercetin With Bromelain 60 Vcaps dropped by 15.4% to $10.49 at AllStarHealth
- Mar 07, 2025Swanson Grape Seed Extract 60 Capsules (only 100mg) dropped by 8.4% to $10.89 at Amazon
- Mar 06, 2025Swanson Grape Seed Extract 120 Capsules dropped by 9.2% to $9.99 at Amazon
- Mar 06, 2025Nutricost Blueberry Extract 180 Capsules dropped by 8.9% to $12.95 at Walmart
- Mar 06, 2025Doctor's Best High Absorption CoQ10 360 Vcaps dropped by 10.3% to $43.31 at iHerb.com
- Mar 06, 2025Swanson Lutein 60 Softgels (only 40mg) dropped by 10.8% to $14.62 at iHerb.com
- Mar 03, 2025NOW Quercetin With Bromelain 120 Vcaps dropped by 7.4% to $17.49 at Muscle and Strength
- Mar 03, 2025Swanson R-Fraction Alpha Lipoic Acid 60 Capsules (only 50mg) dropped by 6% to $15.59 at Amazon
- Mar 03, 2025NOW Quercetin With Bromelain 240 Vcaps dropped by 10.8% to $29.85 at Walmart
- Mar 02, 2025SuperSmart Policosanol 120 Vcaps dropped by 20% to $22.00 at Amazon
- Mar 01, 2025Doctor's Best Lutein & Zeaxanthin Gummies 60 Gummies dropped by 35.1% to $12.00 at AllStarHealth
- Mar 01, 2025Swanson Resveratrol 30 Capsules (only 50mg) dropped by 14.5% to $8.54 at iHerb.com
- Feb 28, 2025KAL Quercetin 60 Tablets dropped by 20% to $22.39 at AllStarHealth
- Feb 28, 2025LifeTime Co-Enzyme Q10 30 Softgels (only 100mg) dropped by 20% to $9.51 at AllStarHealth
- Feb 27, 2025Swanson Maqui Berry, Full Spectrum 60 Capsules dropped by 36.7% to $7.40 at iHerb.com
- Feb 25, 2025Nutricost R-Alpha Lipoic Acid 240 Capsules (only 300mg) dropped by 20.7% to $24.89 at Amazon
- Feb 24, 2025The Vitamin Shoppe Quercetin + C Citrus Free 100 Capsules dropped by 60% to $10.00 at Amazon
- Feb 24, 2025NOW Natural Resveratrol 120 Vcaps dropped by 19.7% to $23.29 at AllStarHealth
- Feb 21, 2025Swanson Onion Bulb, Full Spectrum 60 Capsules dropped by 7.6% to $8.49 at Target.com
- Feb 21, 2025Jarrow Formulas Resveratrol 120 Vcaps dropped by 37.5% to $17.45 at iHerb.com
- Feb 20, 2025Natrium Health OptimALA 60 Capsules dropped by 34.4% to $59.99 at Amazon
- Feb 20, 2025Doctor's Best High Absorption CoQ10 60 Softgels dropped by 11.3% to $10.64 at iHerb.com
- Feb 20, 2025Doctor's Best Lutein 60 Softgels (only with Lutemax 20mg) dropped by 14.8% to $11.24 at iHerb.com
- Feb 18, 2025Genceutic Naturals 24hr CoQ10 60 Vcaps dropped by 18.9% to $25.99 at AllStarHealth
- Feb 18, 2025Natural Stacks Resveratrol+ 60 Vcaps dropped by 11.8% to $16.35 at iHerb.com
- Feb 13, 2025Doctor's Best Ubiquinol 90 Softgels dropped by 11.8% to $24.69 at AllStarHealth
- Feb 12, 2025The Vitamin Shoppe Ubiquinol CoQ-10 30 Softgels (only 100mg) dropped by 9.1% to $18.80 at iHerb.com
- Feb 11, 2025The Vitamin Shoppe Lutein 120 Softgels (only 6mg) dropped by 23.5% to $14.53 at iHerb.com
- Feb 10, 2025Source Naturals Resveratrol 60 Capsules (only 100mg) dropped by 9.8% to $10.09 at VitaCost.com
- Feb 10, 2025NOW CoQ10 180 Vcaps (only 100mg) dropped by 10.2% to $39.19 at Walmart
- Feb 07, 2025SuperSmart Goji Berry Extract 100 Vcaps dropped by 20.8% to $21.00 at Walmart
- Feb 06, 2025The Vitamin Shoppe Quercetin + C Citrus Free 300 Capsules dropped by 56.5% to $10.00 at Amazon
- Feb 05, 2025NOW Pycnogenol 60 Vcaps (only 150mg) dropped by 12.5% to $54.24 at DPS Nutrition
- Feb 02, 2025Source Naturals Pycnogenol and Grape Seed Extract 30 Tablets (only 100 mg) dropped by 9.8% to $19.39 at VitaCost.com
- Feb 01, 2025MRM Superfoods - Organic Fermented Cacao Powder 8.5 Oz. dropped by 15% to $5.60 at AllStarHealth
- Feb 01, 2025MRM Chrysin 30 Vcaps dropped by 8.3% to $14.02 at AllStarHealth
- Feb 01, 2025MRM Resveratrol 60 Vcaps dropped by 15% to $10.65 at AllStarHealth
- Jan 27, 2025NOW Pycnogenol 60 Vcaps (only 30mg) dropped by 15.2% to $13.99 at AllStarHealth
- Jan 27, 2025NOW Pycnogenol 60 Vcaps (only 100mg) dropped by 9.6% to $38.99 at AllStarHealth
- Jan 27, 2025NOW Noni 90 Vcaps dropped by 16.1% to $9.39 at AllStarHealth
- Jan 27, 2025Solaray Mega Quercetin 60 Vcaps dropped by 9.2% to $19.99 at AllStarHealth
- Jan 26, 2025Sunergetic Quercetin & Bromelain 60 Capsules dropped by 12.3% to $14.95 at Walmart
- Jan 21, 2025NOW CoQ10 50 Softgels (only 100mg with Vitamin E) dropped by 8.7% to $10.49 at AllStarHealth
- Jan 21, 2025Nootropics Depot Pomella - Natural Pomegranate Extract 15 Grams dropped by 31.8% to $21.99 at Amazon
- Jan 07, 2025Nootropics Depot CoQH-CF 60 Softgels dropped by 14.6% to $59.99 at Amazon
- Dec 31, 2024Olympian Labs Grape Seed Extract 60 Vcaps dropped by 9.3% to $27.19 at AllStarHealth
- Dec 31, 2024Olympian Labs Grape Seed Extract 100 Vcaps (only 120mg) dropped by 8.9% to $12.74 at AllStarHealth
- Dec 31, 2024Olympian Labs Grape Seed Extract 100 Vcaps (only 400mg) dropped by 9.7% to $28.89 at AllStarHealth
- Dec 31, 2024Paradise Herbs Activin Grape Seed Extract 90 Vcaps dropped by 7.2% to $11.59 at AllStarHealth
- Dec 14, 2024Nootropics Depot NA-R-ALA Stabilized R-Lipoic Acid 30 Grams dropped by 96.5% to $49.99 at Amazon
- Dec 11, 2024Force Factor Apigenin 60 Vcaps dropped by 8.3% to $10.99 at Muscle and Strength
- Nov 24, 2024Source Naturals Resveratrol 60 Tablets (only 500mg) dropped by 18.9% to $29.99 at VitaCost.com
- Oct 27, 2024Body First CoQ10 60 100mg Softgels dropped by 13.6% to $9.50 at AllStarHealth
- Oct 18, 2024Nutricost Astaxanthin 60 Softgels dropped by 9.2% to $18.95 at Amazon
- Oct 16, 2024Doctor's Best High Absorption CoQ10 60 Vegetarian Softgels dropped by 21.4% to $17.32 at iHerb.com
- Oct 08, 2024BODYSTRONG Alpha Lipoic Acid 240 Capsules dropped by 15% to $16.99 at AllStarHealth
- Oct 07, 2024Jarrow Formulas Q-absorb Co-Q10 120 Softgels (only 100mg) dropped by 10.6% to $35.99 at AllStarHealth
- Sep 25, 2024Jarrow Formulas QH-absorb 60 Softgels (only 200mg) dropped by 20.9% to $48.99 at AllStarHealth
- Aug 26, 2024Jarrow Formulas QH-absorb 60 Softgels (only 100mg) dropped by 14.6% to $31.49 at VitaCost.com
- Aug 04, 2024Vitacost Trans-Resveratrol Plus 60 Capsules dropped by 26.5% to $10.48 at VitaCost.com
- Jul 29, 2024NOW CoQ10 180 Vcaps (only 100mg with Hawthorn Berry) dropped by 15.8% to $31.49 at AllStarHealth
- Jul 27, 2024Jarrow Formulas QH-absorb 90 Softgels dropped by 19% to $74.99 at AllStarHealth
- Jul 07, 2024Vitacost Trans-Resveratrol 60 Capsules (only 250mg) dropped by 22.2% to $13.99 at VitaCost.com
- Jul 07, 2024Vitacost Wild Blueberry Extract 120 Capsules dropped by 10.6% to $11.99 at VitaCost.com
- Jul 07, 2024Vitacost Alpha Lipoic Acid 120 Capsules (only 100mg) dropped by 43.8% to $8.99 at VitaCost.com
- Jul 07, 2024Vitacost Acai Berry Extract 60 Capsules dropped by 29.3% to $6.99 at VitaCost.com
- Jul 07, 2024Vitacost Cherry Fruit Extract 180 Capsules dropped by 28.5% to $10.99 at VitaCost.com
- Jul 06, 2024Vitacost Alpha Lipoic Acid 60 Capsules dropped by 18.4% to $7.99 at VitaCost.com
- Jun 23, 2024Healthy Origins Resveratrol 60 Vcaps dropped by 76.7% to $19.99 at Walmart
- Jun 10, 2024Doctor's Best Quercetin Bromelain 180 Vcaps dropped by 12.7% to $22.99 at AllStarHealth
- May 30, 2024Doctor's Best Trans-Resveratrol 100 60 Vcaps dropped by 7.2% to $12.79 at AllStarHealth
- May 30, 2024Doctor's Best Lutein 180 Softgels dropped by 8.9% to $25.49 at AllStarHealth
- May 24, 2024Doctor's Best Noni Concentrate 120 Vcaps dropped by 9.2% to $9.99 at AllStarHealth
- May 16, 2024NOW CoQ10 60 Softgels (only 400mg with Vitamin E & Lecithin) dropped by 16.9% to $30.19 at AllStarHealth
- Apr 16, 2024Country Life R-Lipoic Acid 60 Vcaps dropped by 22.5% to $18.89 at Best Price Nutrition
- Feb 22, 2024Healthy Origins Vegan Ubiquinol 60 Vegetarian Softgels dropped by 9.1% to $29.99 at VitaCost.com
- Feb 19, 2024Country Life Lutein 60 Softgels dropped by 21.4% to $16.49 at VitaCost.com
- Feb 13, 2024Life Extension Super Ubiquinol CoQ10 30 Softgels (only 100mg) dropped by 7.1% to $22.50 at VitaCost.com
- Feb 13, 2024Life Extension Super Ubiquinol CoQ10 30 Softgels (only 200mg) dropped by 8.8% to $39.00 at VitaCost.com
- Feb 05, 2024Solgar Quercetin Complex 50 Vcaps dropped by 10.8% to $11.36 at iHerb.com
- Jan 08, 2024Nutricost CoQ10 120 Capsules dropped by 40.5% to $16.95 at VitaCost.com
- Sep 23, 2023Healthy Origins CoQ10 60 Softgels (only 300mg) dropped by 29.6% to $28.99 at VitaCost.com
- May 26, 2023MRM Grape Seed Extract 100 Vcaps dropped by 36.4% to $12.59 at Best Price Nutrition
- May 19, 2023NutraBio R-Lipoic Acid 60 Vcaps dropped by 10% to $27.00 at NutraBio
- May 17, 2023NutraBio CoQ10 60 Vcaps (only 100mg) dropped by 9.9% to $14.85 at NutraBio
- Mar 09, 2023Jarrow Formulas R-Alpha Lipoic Acid 60 Vcaps dropped by 17% to $17.99 at AllStarHealth
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