Whey protein isolate is a fast digesting, refined form of whey that has been stripped of fat, lactose, and other non-protein constituents, resulting in an end product that consists of 90% or more protein.[1] It provides multiple health benefits and is versatile enough to accommodate most fitness goals, ranging from fat loss to muscle gain.
What is whey protein isolate
Whey protein isolate is a supplemental source of protein that is refined from whey, a byproduct of cheese. It is an exceptional source of dietary protein due to the fact that it contains all nine essential amino acids, making it a complete protein. Additionally, whey protein achieves the highest score possible on the biological value (BV) charts.[2] These charts were established as a way to rate foods according to their protein utilization rates. The aforementioned qualities make whey protein isolate an ideal source of protein, which in some instances can even outperform food sources.
Who should use it
Due to the way it's processed and refined, this form of whey protein can be a particularly good choice for individuals dealing with lactose intolerance.[2] It also serves as a useful option for anyone trying to avoid the additional calories from fats and carbohydrates that are present in other forms of whey.
Benefits
This is a versatile supplement that can aid in achieving a number of fitness goals, as well as provide general health benefits. Numerous studies have been done involving human subjects to prove the efficacy of whey protein isolate. It has been shown to improve body composition, increase strength gains, and promote lean muscle mass.[3,4]. It has also been demonstrated to aid in muscle recovery, combat fat, and decrease cardiovascular risk factors in overweight subjects.[5, 6, 7] Additionally, it has been documented that certain elements in whey protein promote healthy immune function.[2]
Recommended dosage
The Institute Of Medicine (IOM) set the recommended dietary allowance for protein at 56g per day for adult men and 46g per day for adult women. If you are involved in any kind of intense physical exercise or labor, you may want to consult with your health care provider or nutritionist about increasing your daily intake of protein.
Forms
Whey protein isolate is most commonly available in powder form, ready to drink (RTD) products, and protein bars. It is also found as a key ingredient in many protein blends.
Stacks
Process for creating whey protein isolate.
Digestive enzymes
Digestive enzymes will assist in the digestion and absorption of whey protein isolate. This ensures that you are getting the most out of your protein supplement.
Creatine
Athletes who are using whey protein isolate for its strength and mass gain benefits may want to consider stacking it with creatine, an ingredient that is well known to have similar benefits.
Casein
Whey protein isolate by itself is very fast absorbing. In some scenarios it may be beneficial to combine it with casein to achieve more of a well rounded combination of fast and slow digesting proteins. The Journal of Sports Science and Medicine has also suggested that this combination could be beneficial.[2]
Probiotics
Similar to digestive enzymes, probiotics are a smart choice for guaranteeing optimal digestive performance. Proper digestive health is an integral piece of the puzzle when it comes to getting the most out of your supplements.
Side effects
Generally, most of the complications associated with whey protein consumption are only minor. Some of the main issues include:
- Bloating
- Gas
- Digestive discomfort
- Headaches
- Fatigue
While these effects are more common in less purified forms of whey, they may still occur with whey isolate. It is worth it to note that some of these minor side effects may be correspondent with artificial ingredients, such as sweeteners and dyes that are often added to create a better tasting product.
There are, however, more serious side effects associated not with whey protein, in particular, but with a high protein diet in general. In 2001 the American Heart Association published a statement suggesting that individuals following a high protein diet may be at potential risk for cardiac, metabolic, liver, renal, and bone diseases.[2]
Disadvantages
Cost
Generally there are considerable costs involved with the additional filtration techniques required to produce whey protein isolate. This ultimately results in price markups for the consumer. Taking this into consideration, unless you have very specific needs, it may be wise to choose a more cost effective form of whey.
Reduced effectiveness
According to the Journal of Sports Science and Medicine, the manufacturing process involved with producing whey protein isolate may reduce the effectiveness of the protein by destroying the nutrient. This process, known as denaturation, results in broken protein structures and lost peptide bonds.[2]
Food sources
You should always try to be consistent in maintaining a healthy diet. Even though whey protein isolate is a convenient and effective way to supplement additional protein into your diet, it's important to incorporate as many whole food protein sources as possible.
Considerations
Before you begin taking any new supplements, it is important to consult with a health care professional or nutritionist. Additionally, you should always consume a well rounded diet before you consider supplementation.
Warnings
Pregnant women and individuals with preexisting health conditions need to consult with a health care professional about possible contraindications that may occur in result of supplementation with whey protein isolate.
Where to buy
PricePlow provides you with a platform to compare your favorite brands, as well as products that are new to you. Before you make any purchasing decisions, be sure to browse through our unbiased, third party reviews and take advantage of our in depth product guides. We value optimal health and want to help you achieve your goals by providing you with information that will help you to make informed decisions.
What we like
Through our combined experience, we have found that IsoFuel and Bodystrong have the best prices, compared to products in this category. In our opinion Allmax IsoFlex has the best flavor, but it comes with a hefty price.
If you are looking for a nice middle grade product that combines value and quality, we suggest checking out Dymatize ISO-100 or Gaspari Isofusion, both of which have great taste and decent price points for this category.
- When buying your whey protein isolates, be sure to check PricePlow regularly. We update our site every day and post price drops as soon as they happen.
References
- American Dairy Products Institute; "Whey Protein Isolate"
- Hoffman J., Falvo M.; Journal of Sports Science and Medicine; "Protein - Which Is Best?;" September 2004
- Cribb PJ, et al.; International Journal of Sport Nutrition and Exercise Metabolism; "The effect of whey isolate and resistance training on strength, body composition, and plasma glutamine;" October 2006
- Joy JM, et al.; Nutritional Journal; "The effects of 8 weeks of whey or rice protein supplementation on body composition and exercise performance;" June 2013
- Hayes A, et al.; Journal of the International Society of Sports Nutrition; "Whey protein isolate attenuates strength decline after eccentrically-induced muscle damage in healthy individuals;" September 2010
- McAllan L, et al.; the British Journal of Nutrition; "Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes;" December 2013
- Sheikholeslami VD., Ahmadi KGF; Appetite; "Changes in antioxidant status and cardiovascular risk factors of overweight young men after six weeks supplementation of whey protein isolate and resistance training;" December 2012
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Jun 21, 2024 Product News
Myprotein Impact Whey Isolate has new variations: Category: Whey Protein Isolate -
Jun 21, 2024 Product News
Musclesport Lean Whey has new variations: Category: Whey Protein Isolate -
Jun 21, 2024 
Blog Post
MuscleSport Lean Whey Pina Colada: A Tropical Taste for Summer 2024
MuscleSport Lean Whey's NEW Pina Colada delivers a refreshing wave of tropical flavor, while packing the muscle-building power you need to crush your workouts. -
Jun 16, 2024 Product News
Musclesport Lean Whey has new variations: Category: Whey Protein Isolate -
Jun 10, 2024 
YouTube Video
Musclesport Lean Whey Summer Scoops 2024 Flavors Are Here! -
Jun 10, 2024 
TikTok Video
Musclesport’s Summer Scoops Series is back for 2024, available in four flavors: Rocky Road,... -
Jun 08, 2024 
Product News
NutraOne IsolateOne has new variations: Category: Whey Protein Isolate -
Jun 07, 2024 
Blog Post
Musclesport Lean Whey Summer Scoops 2024 Flavors Are Here!
Musclesport's Summer Scoops Series is back for 2024, available in four flavors: Rocky Road, Orange Creme, Pistachio Ice Cream, and Toasted Almond! -
Jun 05, 2024 
Product News
Oath Nutrition Clear Whey Protein was created.
Category: Clear Whey Protein Isolate -
Jun 04, 2024 
Product News
NutraBio Whey Protein Isolate has new variations: Category: Whey Protein Isolate -
May 23, 2024 Product News
Musclesport Lean Whey has new variations: Category: Whey Protein Isolate -
May 17, 2024 
YouTube Video
Kate's Birthday Cake Lean Whey! The REAL Supp Chef at Musclesport? -
May 17, 2024 Product News
Musclesport Lean Whey has new variations: Category: Whey Protein Isolate -
May 17, 2024 
Blog Post
MuscleSport Lean Whey: Kate’s Birthday Cake Celebration Flavor!
MuscleSport is celebrating their very own Kate's birthday by releasing a special Birthday Cake flavor of their Lean Whey protein powder. Happy Birthday Kate! -
May 17, 2024 
TikTok Video
Happy Brithday Kate! It's Kate's Birthday Cake Lean Whey -
May 10, 2024 
YouTube Video
Peach Cobbler Protein?? Musclesport Lean Whey! -
May 10, 2024 
Blog Post
Musclesport Georgia Peach Cobbler Lean Whey Iso Protein!
Musclesport, known for their delicious protein flavors, is at it again with a Georgia Peach Cobbler flavor in their Lean Whey Iso Hydro protein powder. -
May 10, 2024 
TikTok Video
TRY THIS PROTEIN! Georgia Peach Cobbler a La Mode Lean Whey! @musclesportusa just murdered the... -
May 07, 2024 
YouTube Video
GHOST Clear Whey Protein Isolate! Summertime Punch | Sydney Cummings -
May 06, 2024 
Blog Post
GHOST Partners with Sydney Cummings to Unveil Summertime Punch Flavors
GHOST is collaborating with Sydney Cummings for a new Summertime Punch flavor, and it's in a new Clear Whey Protein Isolate product! -
May 03, 2024 
Product News
GHOST Clear Whey Protein Isolate was created.
Category: Clear Whey Protein Isolate -
May 02, 2024 Product News
Musclesport Lean Whey has new variations:- 1 Lb. - Chocolate Ice Cream
- 1 Lb. - Cinna Crunch
- 1 Lb. - Cookies & Cream
- 1 Lb. - DippsAdoodles
- 1 Lb. - Vanilla Ice Cream
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Apr 16, 2024 
Product News
Podium Nutrition Isolate Whey Protein was created.
Category: Whey Protein Isolate -
Apr 14, 2024 
YouTube Video
Protein Flavor of the Year?! Lean Whey CARROT CAKE! -
Apr 14, 2024 
TikTok Video
Protein Flavor of the Year?! @musclesportusa Lean Whey CARROT CAKE! -
Apr 13, 2024 Product News
RAW Nutrition CBUM Itholate Protein has new variations: Category: Whey Protein Isolate -
Apr 12, 2024 Product News
RAW Nutrition CBUM Itholate Protein has new variations: Category: Whey Protein Isolate -
Apr 11, 2024 
Product News
EVLution Nutrition Clear Whey - 100% Whey Protein Isolate was created.
Category: Clear Whey Protein Isolate -
Apr 04, 2024 
YouTube Video
Whey Protein Redefined! AstroFlav IsoMix Updated with BLG-100 -
Apr 04, 2024 
Blog Post
AstroFlav IsoMix: New BLG-100 Reformulation is Out of This World
AstroFlav IsoMix whey protein isolate has been reformulated and upgraded with BLG-100 beta-lactoglobulin for more leucine, now in chocolate & vanilla! -
Mar 29, 2024 Product News
RAW Nutrition CBUM Itholate Protein has new variations: Category: Whey Protein Isolate -
Mar 28, 2024 
Product News
DMoose Fitness Whey Isolate was created.
Category: Whey Protein Isolate -
Mar 26, 2024 
Product News
Flow Supps Protein - Clear Whey Isolate was created.
Category: Clear Whey Protein Isolate -
Mar 22, 2024 
Blog Post
MuscleSport Lean Whey Carrot Cake… Is This a Dessert?!
MuscleSport just dropped a new flavor of their flagship Lean Whey protein powder in Carrot Cake. We got to try this and it tastes just like a dessert! -
Mar 20, 2024 
Product News
Huge Supplements Huge Isolate was created.
Category: Whey Protein Isolate -
Mar 19, 2024 
Product News
Klout PWR was created.
Category: Whey Protein Isolate
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Whey Protein Isolate Price Alerts
The following price alerts are still active:
- Mar 25, 2025Dymatize ISO-100 20 Servings (only Gourmet Vanilla) dropped by 10.9% to $28.50 at Walmart
- Mar 25, 2025Musclesport Lean Whey 2 Lbs. (only Fruity Cereal, Salted Caramel) dropped by 11.9% to $48.45 at Musclesport.com
- Mar 25, 2025Musclesport Lean Whey 2 Lbs. (only Coconut Caramel) dropped by 15% to $48.45 at Musclesport.com
- Mar 24, 2025Nutrex IsoFit 2 Lbs. (only Bananas Foster, Cookies & Cream) dropped by 14.3% to $54.00 at Muscle and Strength
- Mar 24, 2025Nutrex IsoFit 2 Lbs. (only Chocolate Shake, Strawberries & Cream) dropped by 15.6% to $54.00 at Muscle and Strength
- Mar 24, 2025Nutrex IsoFit 2 Lbs. (only Vanilla Bean Ice Cream) dropped by 15.8% to $54.00 at Muscle and Strength
- Mar 24, 2025Dymatize ISO-100 3 Lbs. (only Cocoa Pebbles) dropped by 8.2% to $55.07 at Walmart
- Mar 15, 2025Musclesport Lean Whey 2 Lbs. (only Chocolate Dipped Strawberry) dropped by 11.9% to $48.45 at Musclesport.com
- Mar 07, 2025Jay Robb Whey Protein Isolate 1.5 Lbs. (only Vanilla) dropped by 8.6% to $46.99 at AllStarHealth
- Mar 01, 2025Musclesport Lean Whey 2 Lbs. (only Fluffernutter, Mom's Peanut Butter & Jelly) dropped by 11.9% to $48.45 at Musclesport.com
- Mar 01, 2025Musclesport Lean Whey 2 Lbs. (only Peanut Butter Crunch, Peanut Butter Gone Bananas) dropped by 15% to $48.45 at Musclesport.com
- Feb 26, 2025Dymatize ISO-100 5 Lbs. (only Cocoa Pebbles) dropped by 31.8% to $55.07 at Amazon
- Feb 16, 2025Jay Robb Whey Protein Isolate 1.5 Lbs. (only Chocolate) dropped by 6.4% to $46.99 at AllStarHealth
- Jan 29, 2025Nature's Best Isopure Zero Carb 3 Lbs. (only Chocolate Peanut Butter) dropped by 30.6% to $73.10 at Campus Protein
- Jan 23, 2025Musclesport Lean Whey 5 Lbs. (only Strawberry Ice Cream) dropped by 10.7% to $89.25 at Musclesport.com
- Jan 16, 2025Universal Animal Clear Whey Isolate 5 Servings (only Pineapple Orange) dropped by 49.4% to $4.99 at Supplement Hunt
- Jan 16, 2025Universal Animal Clear Whey Isolate 5 Servings (only Blueberry Acai) dropped by 50.1% to $4.99 at Supplement Hunt
- Nov 29, 2024Muscle Gauge Nutrition Pure Isolate Whey Protein 5 Lbs. (only Chocolate Mint, Peanut Butter, Rocky Road) dropped by 12.2% to $78.99 at Muscle and Strength
- Nov 29, 2024Muscle Gauge Nutrition Pure Isolate Whey Protein 2 Lbs. (only Chocolate Caramel, Chocolate Mint) dropped by 22.2% to $34.99 at Muscle and Strength
- Jul 03, 2024Musclesport Lean Whey 1 Lb. (only Chocolate Ice Cream, DippsAdoodles, Vanilla Ice Cream) dropped by 27.1% to $25.50 at Musclesport.com
Sign up for future Whey Protein Isolate deals and coupons!
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Whey Protein Isolate Reviews & Videos
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Mar 16, 2025Basic MASS: When Simple Nutrition Equals Serious Gains
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Mar 03, 2025Nutristat PÜR NATIVE: The Premium Native Whey Experience
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Mar 03, 2025@nutristat PÜR NATIVE Native Whey delivers superior texture and balanced flavor intensity....
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Feb 27, 2025Why INFORMED Certification Should Guide Your Supplement Choices
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Feb 17, 2025Nutristat PÜR NATIVE Brings True Cold-Filtered Whey Straight From Milk
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Feb 17, 2025The least processed whey you can get @nutristat PÜR NATIVE skips cheese production Straight...
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Feb 14, 2025MuscleSport Clean Whey Naturals Strawberry Ice Cream
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Feb 14, 2025AN Performance Hybrid Protein Features Chiquita and Informed Protein Certifications
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Feb 14, 2025Victoria tries @musclesportusa Clean Whey Naturals Strawberry Ice Cream No artificial...
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Feb 13, 2025MuscleSport Clean Whey Naturals Chocolate Ice Cream
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Feb 13, 2025Heavy Metals in Dietary Supplements: Basic Supps Sets New Industry Standards
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Feb 13, 2025Clean protein that tastes like melted Frosty? Cody tries @musclesportusa Clean Whey Naturals ...
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Feb 12, 2025MuscleSport Dominates 2024 as PricePlow's Protein Brand of the Year
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Feb 12, 20252024 PricePlow Protein of the Year goes to @musclesportusa Monthly flavor drops that never...
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Jan 27, 2025Whey ISOLATE That Wows! Basic Supplement PEANUT BUTTER COOKIE
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Jan 27, 2025Think whey isolate is thin and flavorless? @getbasicsupps just flipped the script. With 26g...
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Jan 21, 2025TASTE TEST: RTDs Made with Arla Foods Ingredients Protein Sources
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Jan 16, 2025Basic Supplements Goes Full Transparency with Third-Party Lab Test Results
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Jan 15, 2025What If Your Energy Drink Came With 10g of Protein?
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Jan 15, 2025Animal Isolate Loaded Whey Protein Now in Caffeinated Cold Brew Latte Flavor!
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Jan 10, 2025Animal's NEW Cookies & Cream Whey Keeps Their Hardcore Spirit
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Jan 07, 2025MuscleSport's Nana's Banana Cream Pie Lean Whey: Perfect Balance of Banana and Cream
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Jan 07, 2025@musclesportusa nails it again! Nana's Banana Cream Pie Lean Whey delivers sweet banana flavor...
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Dec 20, 2024C4 Whey Hershey's Protein Review! Real Hershey's Cocoa
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Dec 16, 2024MuscleSport Lean Whey: Christmas Flavors You’ll Love
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Dec 16, 2024These Christmas flavors are insane by @musclesportusa
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Dec 11, 2024MuscleSport Lean Whey: Peanut Butter Crunch and Mom’s Peanut Butter & Jelly
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Dec 11, 2024@musclesportusa Lean Whey brings peanut butter bliss with four flavors! Victoria highlights PB...
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Dec 09, 2024Mosh Bar: A Brain and Body Fuel Protein Bar with 125mg Cognizin® Citicoline!
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Dec 02, 2024Fluffer Nutter & Peanut Butter Gone Bananas: MuscleSport’s Lean Whey Delights!
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Dec 02, 2024@musclesportusa Lean Whey brings 2 of its 4 peanut butter flavors to the spotlight: Fluffer...
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Nov 09, 2024Musclesport’s Lean Whey Launch: Come At Me Cannoli for The Supp Chef’s Birthday
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Nov 09, 2024Mike’s take? @musclesportusa’s Come At Me Cannoli Lean Whey, launched for @thesuppchef’s...
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Nov 08, 2024Musclesport’s Lean Whey Launch for The Supp Chef’s Birthday | Chocolate Chip Oatmeal Cookie
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Nov 08, 2024Happy Birthday, @thesuppchef! @musclesportusa is celebrating with two new flavors: Cannoli and...
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Oct 31, 2024C4 Whey! The Hershey Reese’s Peanut Butter Collab Reviewed
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Oct 21, 2024Magnum Nutraceuticals Whey 100+: A Budget-Friendly Alternative to Quattro
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Oct 17, 2024Lacprodan® BLG-100: 21g of Protein in a 3oz Shot
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Oct 12, 2024Monster Cookie Madness: MuscleSport Lean Whey’s Must-Try Blue Protein!
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Oct 12, 2024@musclesportusa Lean Whey Monster Cookie flavor is dropping 10/11! Packed with chocolate chips,...
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Sep 28, 2024Clean Simple Eats Clear Protein in a Can
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Sep 28, 2024How does @cleansimpleeats compare to the competition?
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Sep 24, 2024Musclesport Releases New Italian-Themed Flavors for Lean Whey and Amino + Hydration!
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Sep 24, 2024@musclesportusa just dropped new Italian-themed Lean Whey flavors: Come At Me Cannoli and...
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Sep 06, 2024MuscleSport Lean Whey Pumpkin Spice Welcomes Fall 2024
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Sep 06, 2024Smaller Sized MuscleTech Nitro-Tech 1.5Lb Tubs (with Creatine) Now at Walmart
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Sep 06, 2024@musclesportusa is back with their seasonal Lean Whey flavor: Pumpkin Spice!
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Aug 28, 2024Arla Foods Ingredients Making the Perfect Product for You
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Aug 28, 2024What are the Top 5 Musclesport Lean Whey Protein Flavors?
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Aug 28, 2024Muscletech Nitro Tech Whey Gold Limited Edition Chocolate Peanut Butter & Banana Cream Flavor!
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